Rejuran vs Skin Botox: which should you address first—shine and pores, or dry skin texture?

Even people with the same pore concern may want different results. If shine is the main issue, record when oiliness bothers you during the day and how you use blotting papers. For pore appearance, take photographs under the same lighting and from the same angles. For dry surface texture, separately record tightness, flaking, irritation and moisturization. This helps organize an individual consultation; it is not a validated self-diagnosis scorecard. Less sebum does not mean more skin hydration, and improvements in texture or pore volume do not establish sebum suppression. In the 2026 Rejuran Healer study, both injection methods improved pores and texture, but hydration and sebum did not change significantly. What matters is whether your goal matches what the study measured, rather than following a rule that oily skin always needs toxin and dry skin always needs PN.

Rejuran PN injections and Skin Botox differ in their ingredients and the purpose of delivery. Skin Botox and microbotox are terms for injecting botulinum toxin in small amounts at multiple sites within the skin; they do not refer to the specific brand BOTOX. They are also distinct from intramuscular injections for ordinary expression lines. Do not use the names PN and PDRN interchangeably, or cite studies as though topical application, application after microneedling and intradermal injection were interchangeable. Check the exact product, injection layer, site, actual amount and approved uses in Korea. US approval of intradermal BOTOX injections for underarm hyperhidrosis does not mean approval for facial sebum or pore treatment.

Read the evidence separately for each goal. In a 2025 randomized trial of 36 women, incobotulinumtoxinA 20U or saline was injected intradermally into the middle and lower face; 33 participants completed the study. Sebum changes at day 28 and pore measures at days 28 and 56 favored toxin, but the small sample had mask-related skin quality concerns, so the findings cannot be applied to all oily skin. A 2017 pilot trial of 10 women found improved texture but no significant reduction in sebum or pores. A 2026 split-face study of 30 people injected Rejuran Healer three times at 4-week intervals, using an intradermal needle on one side and a subcutaneous cannula on the other, and assessed participants for up to 5 months. Pores and texture changed on both sides, but there was no untreated control, the instrument and injection layer differed together, and the study received manufacturer support. Combining these studies cannot establish whether PN or toxin is better or how long their effects last.

Adults who can describe their main concern—oiliness, pore appearance or dry surface texture—can seek a consultation. Report dermatitis, infection, active inflammation, allergies to fish or injection ingredients, previous nodules or persistent swelling, bleeding-related medical history and medications, and pregnancy or breastfeeding. If considering toxin, also review the product, units and dates of recent toxin treatments elsewhere, neuromuscular disorders, swallowing or breathing problems, and medications that may interact. If the skin is red, stinging or severely flaky, assessing the cause may take priority over choosing an injection.

At the consultation, summarize the target area, measure to change and assessment timing in one line, and obtain a product-specific plan and quote. If you choose treatment, anesthesia, disinfection, injection and follow-up are carried out according to your skin's condition. Bruising, swelling, raised injection-site wheals and tenderness may last several days or longer. Record each PN product's amount separately from the toxin's units, dilution and sites; do not compare liquid volume as a shared unit of effect. Do not judge immediate shine or swelling as the final result. At the agreed time, review photographs taken under the same conditions and changes in discomfort. If the desired change does not occur, or dryness or functional problems develop, reassess the goal and plan instead of repeating treatment automatically.

Injections can cause pain, bruising, swelling, infection, hypersensitivity reactions, persistent papules or nodules, and other problems. Toxin carries additional risks, including unwanted muscle weakness, asymmetry at the corners of the mouth, changes in smiling or speech, and drooping eyelids. A shallow injection or small amount alone cannot guarantee that your smile will be unaffected. Severe pain, abnormal skin color, vision changes, difficulty swallowing, speaking or breathing, or generalized muscle weakness require immediate medical attention. The absence of serious adverse events in small studies does not establish that rare risks are absent.

These questions for a consultation before visiting SEOLREIM are based on the literature. They are not a clinician interview or an individual prescription. This new article is awaiting confirmation of a separate review by a medical professional.

Q. If my pores are large, should I have Skin Botox before Rejuran?

A. First assess why the pores are noticeable and whether oiliness is also a concern. Intradermal toxin has been studied for sebum, but results are inconsistent, and reducing sebum does not mean treating every pore problem or indented scars.

Q. Does PN always increase hydration in dry skin?

A. This cannot be guaranteed. A comparison of PN and HA around the eyes found hydration-related signals, but the 2026 pore study found no significant change in hydration. The sites, products, participants and comparison groups differed, so consider the findings alongside basic moisturizing care and assessment for dermatitis.

Q. Will shallow Skin Botox leave my smile unchanged?

A. Shallow placement alone does not guarantee preservation of facial expressions. At your consultation with the SEOLREIM clinic director, demonstrate the movements you want to retain and any existing asymmetry. Discuss the sites, total units and spread risk, as well as adjusting the treatment area or deferring treatment.

SEOLREIM Clinic in Gangnam reviews priority goals and actual treatment details through consultations and procedures performed directly by the clinic director, guided by its principles of authentic products, correct amounts and attentive care. Shining Rejuran, Royal Rejuran and Silky Pore Injection on the official menu are signature programs you can discuss for skin quality and pore concerns. Do not assume from their names that they use the same product, ingredients or method as the Rejuran Healer study, or that Silky Pore Injection contains toxin. Confirm the actual Skin Botox product, availability and scope, and price before booking. Do not apply a paper's findings to an entire signature program; ask the director why each component is needed and for a plan that starts with one option.

If comparing Rejuran and Skin Botox at a dermatology clinic in Gangnam, first identify one change you want in oiliness, pores or dry texture, before looking at glowing-skin reviews of Seoul dermatology clinics. International visitors preparing to visit a dermatology clinic near Gangnam Station or elsewhere in Korea should send this goal and records of previous injections to SEOLREIM's consultation team, and ask about the actual treatment scope and how follow-up is assessed. The official guidance for international patients lists consultation support from on-site English- and Chinese-speaking staff and interpretation in 14 languages with advance booking; an appointment is required before visiting. SEOLREIM Clinic is on floor 11 of the Gangnam 8258 Building, 376 Gangnam-daero, Seoul, approximately 1 minute from Gangnam Station Exit 3. For Korean-language consultations and bookings, use the KakaoTalk, Naver Booking or telephone channels below; for consultations about an international visit, use the International consultation link. Provide your treatment interests, skin concerns, dates of your stay in Korea, preferred language and whether you need an interpreter. Before visiting, confirm actual language support, costs, booking confirmation and cancellation terms. Depending on the examination, same-day treatment may not be possible, or follow-up may be needed after you return home, so also discuss how to contact the clinic about adverse reactions and the actual scope of aftercare.

Study comparing Rejuran PN injection methods in 30 participants (2026): https://doi.org/10.1111/jocd.70946 ; Randomized trial of intradermal incobotulinumtoxinA versus saline in 36 participants (2025): https://pubmed.ncbi.nlm.nih.gov/40847901/ ; Pilot trial in 10 participants that found no significant reduction in sebum or pores (2017): https://pubmed.ncbi.nlm.nih.gov/28367260/ ; Comparison of PN and non-cross-linked HA in 27 participants: https://pubmed.ncbi.nlm.nih.gov/32248707/ ; Product-specific precautions on delivery route, spread and units: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=485d9b71-6881-42c5-a620-a4360c7192ab . Do not interpret separate studies as a direct comparison of PN and toxin. Evidence and official information checked: 2026-10-27.

Related article: Skin Botox and microbotox benefits and side effects: limitations for pores, sebum and fine lines https://www.sulskin.co.kr/pages/ko/product-288 / Are Silky Pore Injection, Juvelook and Skin Botox all the same pore injection? How to check ingredients and goals https://www.sulskin.co.kr/pages/ko/product-370 / Can Rejuran replace Botox? How to choose fine-line treatments in Korea https://www.sulskin.co.kr/pages/ko/product-390 / Rejuran versus hydration injections: is skin regeneration or improved hydration right for you? https://www.sulskin.co.kr/pages/en/product-136

Written by: SEOLREIM Content Editor (AI-assisted writing) / Literature and image editorial review: 2026-10-27 / Medical reviewer: not assigned · Medical review not completed / Published and updated: 2026-10-27. This is general medical information and does not replace an individual diagnosis or prescription.