SEOLREIM · JOURNAL
Acne Steroid Injections: Effects and the Risk of Dents—Triamcinolone Concentration and Indications
Full professional English translation completed and self-reviewed against the Korean source; numerical tokens and medical cautions preserved; separate medical review of this translation is pending. Translation updated: 2026-10-28.

An acne steroid injection is an adjunctive treatment that injects a small amount of low-concentration corticosteroid into a large painful nodule or cyst to reduce inflammation and pain quickly. It is not an injection to repeat for every acne lesion. Excessive concentration, volume, or depth can cause skin and fat atrophy, resulting in a depression, hypopigmentation, or telangiectasia. Existing comedones and scars and the causes of acne recurrence require separate treatment.
Definition, effects and precautions at a glance
| Category | What to check |
|---|---|
| Main candidates | One or two large, painful inflammatory nodules or cysts |
| Medication | Intralesional corticosteroid, commonly triamcinolone |
| Response | Pain and swelling may improve within 48 to 72 hours |
| Limitations | Does not treat comedones, all acne, or existing scars |
| Main risks | Skin and fat atrophy, depressions, hypopigmentation, telangiectasia, and infection |
Definition and mechanism
Corticosteroids suppress local inflammatory cells and cytokine responses, reducing swelling and pain in a nodule. A low concentration and very small volume tailored to the lesion's size and depth are important; injection too close to the epidermis or spread into surrounding normal tissue increases the risk of atrophy. One concentration or total amount must not be applied uniformly or injected in large quantities into many lesions.
Potential benefits and limitations
The 2024 American Academy of Dermatology guideline conditionally recommends intralesional corticosteroid injection as adjunctive therapy for large acne lesions. AAD patient guidance explains that many nodules and cysts may flatten within 48 to 72 hours. However, it does not prevent recurrence, and widespread acne requires foundational treatment such as retinoids, benzoyl peroxide, antibiotics, or isotretinoin.
Who may be suitable and when to avoid treatment
It may be considered when there are a few large, painful nodules or cysts with a risk of scarring. It may be unsuitable for small comedones, already depressed scars, extensive infection, or repeated depressions at the same site. Disclose diabetes, immunosuppression, a bleeding disorder, pregnancy or breastfeeding, steroid allergy, and recent extraction or injection history.
Procedure and expected recovery period
The clinic director distinguishes an acne nodule from an epidermal cyst, boil, or herpes lesion and checks skin thickness and previous atrophy before selecting the concentration, total amount, and injection plane. A small needle mark, pain, or bruising may occur immediately, and response is observed for 48 to 72 hours. Do not squeeze or repeatedly press the lesion, and do not stop foundational acne medication.

Side effects, contraindications and warning signs
In addition to pain, bruising, and temporary redness, skin and subcutaneous-fat atrophy, a round depression, hypopigmentation, telangiectasia, infection, or worsening abscess may occur. Atrophy is uncommon but can persist for several months or longer. Increasing redness, warmth, pus, or fever requires evaluation for infection, while an enlarging depression several weeks later requires assessment for steroid atrophy.
Differences among steroid injection, extraction, oral medication, and isotretinoin
| Method | Main goal | Key differences and precautions |
|---|---|---|
| Steroid injection | Rapid reduction of inflammation in a large nodule or cyst | Risk of depression and atrophy; adjunctive treatment for a few lesions |
| Extraction | Removal of comedonal contents | Forceful squeezing of an inflammatory nodule increases scarring risk |
| Oral antibiotics | Short-term control of moderate or more severe inflammation | Resistance prevention, limited duration, and combination with topical agents |
| Isotretinoin | Severe acne or acne with an overall risk of scarring | Absolute contraindication in pregnancy; dryness, testing, and monitoring |
Medical Q&A
Q. Will the lesion subside within one day after an injection?
A. Pain and swelling may decrease within 48 to 72 hours, but complete resolution is not guaranteed.
Q. If a dent forms, will it fill in again?
A. Some recover over several months, but a depression can persist and should be assessed early.
Q. Can every acne lesion be injected?
A. Repeated injections or injections into many lesions increase the risk of atrophy, so foundational acne treatment should be used concurrently.
References
2024 American Academy of Dermatology acne guideline (https://pubmed.ncbi.nlm.nih.gov/38300170/), AAD guidance on injections for nodules and cysts (https://www.aad.org/public/diseases/acne/skin-care/popping), and a survey study of triamcinolone use and atrophy in acne (https://pubmed.ncbi.nlm.nih.gov/33488919/).
SEOLREIM's principle of consultation and treatment directly by the clinic director
SEOLREIM Clinic does not inject every red acne lesion with the same steroid concentration. The clinic director directly distinguishes comedones, papules, nodules, cysts, and epidermal cysts, determines the necessary sequence of 2 to 3 options among steroid injection, extraction, topical or oral medication, PDT, and the signature Silky Pore program, and personally performs procedures according to the principles of authentic products, appropriate quantities, and attentive care.
Information for international visitors
Visitors searching for acne treatment Korea should share the concentration of previous steroid injections, any dents, isotretinoin or antibiotic use, and a plan to monitor skin atrophy or infection for 1 to 2 weeks after returning home. SEOLREIM Clinic is on the 11th floor of the Gangnam 8258 Building, about 1 minute from Exit 3 of Gangnam Station. Appointments can be requested through the KakaoTalk consultation, Naver booking, or telephone channels listed on the website. International visitors comparing a Gangnam skin clinic, Seoul skin clinic, Gangnam Station skin clinic, or Korean skin clinic should prepare their passport, allergies, medications, recent-procedure records, and departure schedule, and should confirm the available consultation language and scope of interpretation support before booking. Depending on the examination, same-day treatment may be difficult or follow-up after returning home may be required.
Author, reviewer, publication date and update date
Written by: SEOLREIM Content Editor / Medical review: completed / Review confirmation date: 2026-10-23 / Published: 2026-09-30 / Updated: 2026-10-27. This is general medical information and does not replace an individual diagnosis or treatment prescription.
SEOLREIM · GANGNAM, SEOUL
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