Are Swelling and Raised Bumps Normal After Rejuran? Results, Recovery, and Precautions

Rejuran, Rejuran benefits, Rejuran side effects, Rejuran treatment intervals, skin boosters, Gangnam dermatology clinic · Rejuran Seoul · Rejuran in Seoul · Skin Booster Seoul

Rejuran is a skin booster that injects PN (polynucleotides) into the skin. Rather than adding volume like a filler, it aims to improve skin condition and the environment for recovery.

Improvements in texture, fine lines, dryness, and reduced firmness may be expected. However, it does not directly lift deep wrinkles or sagging, or remove scars in one session. Research findings and perceived results vary among individuals.

People with thin, dry skin, fine lines, or rough texture may consider consultation. Active inflammation or infection should be treated first.

After consultation and skin assessment, anesthesia, disinfection, and injection follow. Redness, raised bumps, bruising, and tenderness may occur immediately afterward. Recovery varies by area and individual.

Pain, swelling, bruising, and redness are common possibilities. Seek immediate care for worsening pain, skin-color changes, blisters, heat, or pus. Disclose pregnancy or breastfeeding, skin infection, medications that increase bleeding risk, and ingredient allergies beforehand.

Rejuran focuses on PN-based improvement of the skin environment; hydration injections mainly use hyaluronic acid for moisture and texture; fillers primarily restore volume and contours in specific areas. Even within skin boosters, ingredients and purposes differ.

Recurring questions include: 'Does no raised bump mean no effect?', 'Can I work the next day?', 'Can Rejuran be injected under the eyes?', 'Is 1 session enough?' and 'Does more pain mean better results?' Raised bumps alone cannot determine effectiveness. Recovery and results vary, so confirm the injection areas and product with your clinician.

Q. Is 1 session enough? A. Response can be assessed after 1 session, but the number and interval depend on the product, skin condition and goal. Q. Can it be combined with hydration injections? A. Combination may be possible, but same-day treatment and sequence are determined after examination. Q. Can topical products at home replace it? A. Moisturizers and injections have different delivery methods and cannot be considered equivalent.

References include an expert consensus on PN (PubMed PMID 32799391), a systematic review of hyaluronic acid injection safety and adverse events (PubMed PMID 30636365), and an international consensus on cosmetic injection complications (PubMed PMID 27219265). Research varies by product and injection method and does not guarantee individual results.

Medically reviewed · Confirmed 2026-10-30 · General medical information; not a substitute for an individual diagnosis or prescription.

SEOLREIM Clinic does not simply repeat a fixed Rejuran dose. We assess skin thickness, sensitivity, dryness, fine lines, reduced firmness, and the condition of the eye and cheek areas before planning injection sites and depths. Before treatment, we explain possible bumps and bruising, recovery time, and scheduling around important events. Afterward, we provide guidance on cleansing, makeup, exercise, alcohol, and adverse reactions. Our signature Shining Rejuran and Royal Rejuran may be discussed alone or with other skin-improvement programs according to your concerns and goals.

SEOLREIM Clinic is a skin and aesthetic clinic that has provided care in Gangnam, Seoul since 2011. Consultations and procedures performed directly by the clinic director form the basis of plans tailored to individual skin conditions. Treatment effects and recovery vary, so final decisions follow an in-person examination.